Small Molecules to Facilitate Chemotherapeutic Delivery

نویسندگان

  • Gregory Allen Ellis
  • Gregory A. Ellis
  • Ronald T. Raines
  • John M. Denu
  • Samuel H. Gellman
چکیده

............................................................................................................................... i Acknowledgments .............................................................................................................. iv List of Tables ................................................................................................................... xiv List of Schemes ................................................................................................................. xv List of Figures .................................................................................................................. xvi List of Abbreviations ....................................................................................................... xix CHAPTER

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

راهبرد‌های افزایش نفوذ در دارورسانی پوستی

Transdermal drug delivery (TDD) is a non-invasive, topical administration method for therapeutic agents. Transdermal delivery also has advantages including providing release for long periods of time, improving patient compliance, and generally being inexpensive. Despite these advantages, the use of TDD has been limited by innate barrier functions of the skin. Only small (<500 Da), lipophilic mo...

متن کامل

Biol. Pharm. Bull. 28(2) 387—390 (2005)

systems, having been investigated for delivery of chemotherapeutic agents for cancer, vaccines for immunological protection, radiopharmaceuticals for diagnostic imaging, and nucleic acid-based medicines for gene therapy. As is observed for colloidal drug delivery systems, however, the physico-chemical stability of liposomes varies with their compositions and structures. In most cases liposomes ...

متن کامل

Recent advances in nanoformulations for co-delivery of curcumin and chemotherapeutic drugs

The application of chemotherapy in cancer treatment has been limited due to cause side effects such as toxicity against normal cells and drug resistance. In recent years, numerous studies have been focused on using natural products with chemotherapeutic drugs to enhance therapeutic efficiency and reduce cytotoxicity. On the other hand, encapsulation of drugs into nanoparticles (NPs) can improve...

متن کامل

Pharmaceutical Nanocarriers (Liposomes and Micelles) in Cancer Therapy

Fundamental progress in cancer biology has resulted in remarkable advances in diagnosis and cancer therapy. The need now is to transform this knowledge into effective therapies. The effectiveness of chemotherapeutic drugs is severely limited due to the dose-limiting toxicity and patient morbidity. In cancer therapy, effective delivery of the drug to the tumor site while avoiding off-site side e...

متن کامل

Controlled drug release to cancer cells from modular one-photon visible light-responsive micellar system.

We present a one-photon visible light-responsive micellar system for efficient, on-demand delivery of small molecules. Release is mediated by a novel class of photochromic material - donor-acceptor Stenhouse adducts (DASAs). We demonstrate controlled delivery of small molecules such as the chemotherapeutic agent (paclitaxel) to human breast cancer cells triggered by micellar switching with low ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2012